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Description

Many studies have reported that the downregulation of PGC-1 was associated with abnormal mitochondrial biogenesis and diminished ATP production capacity, and the reduced mitochondrial biogenesis in hepatocytes by silica nanoparticles was also associated with the inhibition of the PGC-1/NRF-1/TFAM pathway (81)

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2006;290(4):R103543

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